IPharm Animal Research Facility (IPARF) is designed and built to meet the international standards of the Organisation for Economic Co-operation and Development Good Laboratory Practice (OECD-GLP) and the Association for Assessment and Accreditation of Laboratory Animal Care (AAALAC) to carry out pre-clinical animal studies and Specific Pathogen-Free (SPF) rodent breeding program. IPARF is a separate building next to the IPharm main buildings and it is operated as a restricted-access facility since 2011. The facility has an area of approximately 4000 square meters with animal holding rooms, SPF rodent breeding rooms, cleanroom (class 10,000), surgical room, procedure rooms, Animal Biosafety Level 2 (ABSL 2) laboratory, quarantine room and necropsy rooms. This facility houses equipments such as individually ventilated cages, rotarod testing system for rodents, grip strength testing system for rodents, high capacity steam sterilizers, rack and cage washer and animal drinking bottle station to support preclinical studies and SPF breeding activities.
Besides the capability in carrying out GLP toxicity study, researchers can also utilise the facility for the non-GLP animal studies. At present, IPARF is also working closely on collaborations with a biotechnology company and Universiti Sains Malaysia for its SPF rodent breeding program. We have initiated the actions towards achieving the AAALAC accreditation and aiming at providing high quality SPF rodents and animal models to interested parties. All research proposals on animal studies and breeding program will be thoroughly reviewed by the IPharm Animal Ethics Committee (IPAEC) to ensure that all activities comply with the animal research legislation and ethical conduct.